The following is a listing from SAA of active third party spondylitis research opportunities. SAA is not affiliated with these studies, and is sharing them as a service to the community.
A phase 3 clinical trial is now recruiting axial spondyloarthritis (ankylosing spondylitis) patients over the age of 18 to take part in a three-pronged study. The investigational study medication is an IL-17 inhibitor called Ixekizumab.
Eli Lilly and Company, who is the drug manufacturer and is sponsoring the study, has created a website where you can learn more, and prescreen for each of the studies. See “Find a Lilly Trial.”
The three related studies can also be found through ClinicalTrials.gov, linked below:
Learn more about participating in Clinical Studies.
The University of Wisconsin, Madison is studying blood type distribution in patients with certain autoimmune / autoinflammatory conditions, including ankylosing spondylitis.
If you are a patient formally diagnosed with ankylosing spondylitis and know your blood type, the study investigators ask you to complete an anonymous online survey that asks only two questions: Blood Type and Country of Birth.
Additional Study Information
Study details and background
Study IRB approval
Note from SAA: We are delighted to inform you of this study led by Dr. James Rosenbaum, current member of SAA’s Medical and Scientific Advisory Board.
Recent scientific studies have shown that the bacteria and other organisms which normally reside in our gut can have a profound effect on the immune system and inflammatory disease. This study will analyze gut microbe data to determine if there are patterns or certain associations with ankylosing spondylitis or HLA-B27.
Participants will be asked to complete a questionnaire, keep a 2-day food diary and to provide a sample of feces (stool) which can be collected at home and shipped to our research laboratory. An optional sample of saliva may also be provided. There are no costs for participation and all sample packaging and shipping materials are provided. If you choose to be in the study, you will not personally benefit, but may help to benefit patients with ankylosing spondylitis in the future.
For more information, please contact Dr. Rosenbaum’s research team at 503-494-5711 or B27microbiome@ohsu.edu. Thank you!
Oregon Health & Science University
PA: James Rosenbaum, MD
Relationship between HLA B27, disease status and gut microbes (An extension study of “Influence of HLA B27 status and colonoscopy bowel prep on the gut microbiome in conjunction with analysis of the gut microbiome along the gastrointestinal tract”)
PO Box 5872
Sherman Oaks, CA 91413
(800) 777-8189 U.S. only
or (818) 892-1616