FDA issues suicide caution for antidepressants
3/22/2004
From: CNN.com, March 22, 2004
The FDA has stated that patients on some popular antidepressants should be watched carefully for the warning signs of suicide. The Food and Drug Administration has also asked the makers of 10 drugs to add the caution to their labels.
Although it isn’t clear yet if the drugs actually do lead to suicide, the FDA has called for stronger warnings to doctors and patients that the antidepressants may cause agitation, anxiety and hostility in a subset of patients who may be unusually prone to rare side effects. The FDA’s initial investigation into the possible suicide connection focused on children given the drugs, but the warning is aimed at both adult and pediatric use of the pills.
The drugs in question are: Prozac, Paxil, Zoloft, Effexor, Celexa, Remeron, Lexapro, Luvox, Serzone and Wellbutrin. Most of these newer-generation antidepressants are known to affect the brain chemical, serotonin.
According too the FDA, in 2002, nearly 11 million prescriptions were given to patients under 18 for SSRIs and other antidepressants to treat depression and a host of other conditions.