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A study that was published in Oxford Journals was conducted "to evaluate the efficacy and safety of etanercept 100 vs 50 mg/week in patients with AS." In the study, "adult patients with AS were randomized to receive etanercept 50mg twice a week, or etanercept 50mg once a week for 12 weeks."
The study concluded that "high-dose (100mg/week) etanercept in the treatment of AS for 12 weeks is as safe as the standard dose (50mg/week). However, it does not significantly increase its efficacy."
To read the study abstract, click here.
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