Clinical Trial Opportunity for Adults with Ankylosing Spondylitis

By Spondylitis Association of America

Monday, April 9, 2018

The following is an announcement from SAA about a third party clinical trial. SAA is not affiliated with this study, the researchers, or the drug manufacturer.


A phase 2/3 clinical trial is now recruiting patients over the age of 18 with active ankylosing spondylitis (AS) to participate in a study evaluating the safety and efficacy of Upadacitinib (ABT- 494) - a JAK inhibitor medication taken orally.

The purpose of the trail, titled, “A Study Evaluating the Safety and Efficacy of Upadacitinib in Subjects With Active Ankylosing Spondylitis” is to investigate the effectiveness, impact and performance of Upadacitinib by comparing the perceived symptomatic improvements in pain, global assessment, function, and inflammation experienced with Upadacitinib versus a placebo (a mock medication with no therapeutic effects.)

Study qualifications include:

  • •  Age 18-99.
  • •  Have a clinical diagnosis of ankylosing spondylitis.
  • •  Have experienced an inadequate response to at least two Nonsteroidal Anti-Inflammatory Drugs (NSAIDs).
  • •  Have had no exposure to any biologic medications used for spondyloarthritis.

More information can be found on the Clinical Trials website.

This study is sponsored by AbbVie, who has created a promotional website for the study. You’ll find additional information and a qualification questionnaire at

For location of study centers, you can call (847) 283-8955, email or visit the clinical trials study locations page.


Learn more about participating in Clinical Studies



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