Clinical Trial Opportunity for Adults with Ankylosing Spondylitis

By Spondylitis Association of America

Friday, July 27, 2018

The following is an announcement from SAA about a third party clinical trial. SAA is not affiliated with this study, the researchers, or the drug manufacturer.


A phase 4 clinical trial is now recruiting patients over the age of 18 with active ankylosing spondylitis (AS) to participate in a study evaluating the clinical difference between 300 mg and 150 mg of secukinumab.

The purpose of the trial, titled, “Study Estimating the Clinical Difference Between 300 mg and 150 mg of Secukinumab Following Dose Escalation to 300 mg in Patients With Ankylosing Spondylitis (ASLeap)” is to investigate the effectiveness, impact, and performance of different secukinumab doses by comparing the effects of 150 mg and 300 mg.

Study qualifications include:

  • •  Over the age of 18.
  • •  Have a clinical diagnosis of moderate to severe ankylosing spondylitis.
  • •  Have a Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) >= 4.
  • •  Be on non-steroidal anti-inflammatory drugs (NSAIDs) at the maximum tolerated dose for at least 4 weeks prior to their Baseline Visit with an inadequate response, or for less than 4 weeks if withdrawn for intolerance, toxicity or contraindications.

More information can be found on the Clinical Trials website.

This study is sponsored by Novartis who has created an informational website for the study. You’ll find additional information, including qualification criteria and participating sites at

You can also call (866) 244 - 9578, email, or visit the clinical trials study locations page.


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